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Barbara JobstBarbara C. Jobst, MD, Dr. med, FAAN
Barbara C. Jobst, MD, Dr. med, FAAN
Professor of Neurology
Geisel School of Medicine at Dartmouth
Director, Dartmouth-Hitchcock Epilepsy Center
Department of Neurology
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
(603) 653-6265
(603) 650- 6233 (fax)
Barbara.C.Jobst@Hitchcock.org

Barbara C. Jobst, MD is currently Professor of Neurology and Director of the Dartmouth-Hitchcock Epilepsy Center.  The Dartmouth-Hitchcock Epilepsy Center is the only level 4 epilepsy center in Northern New England, and serves a large rural population of epilepsy patients. Dr. Jobst has extensive experience in the clinical care, psychosocial consequences and surgical treatment of epilepsy patients. She has extensively published on the clinical characteristics of frontal and other neocortical epilepsies and the utilization of brain stimulation for the treatment of epilepsy. She has conducted multiple clinical research studies and has ample experience with clinical research e.g. in brain stimulation and the treatment of epilepsy with progesterone, which was funded by federal agencies as well as other sources.

She also studies the underlying pathophysiology of memory dysfunction from a basic science and clinical research point of view, trying to explore underlying neuronal processes of memory dysfunction and cognition with single cell recordings in humans. This research is funded by the National Institute of Health and the Department of Defense. While studying the pathophysiology of memory processes is exciting, she realized that an intervention is urgently needed to improve memory in this particular patient population.  Screening for memory impairment has been implemented at the Dartmouth-Hitchcock Epilepsy Center clinics for several years, and has demonstrated that a memory intervention is urgently needed so patients can live well with epilepsy.
Dr. Jobst is the Principal Investigator of the Managing Epilepsy Well Network, which is a community of practice for self-management in epilepsy.

She and her team at Dartmouth developed HOBSCOTCH (HOme Based Self-management & COgnitive Training CHanges lives), a program that uses self-management strategies to improve subjective and objective memory function in patients with epilepsy.  This program teaches problem-solving strategies and compensatory mechanisms to help manage cognitive dysfunction and enhance quality of life.  At Dartmouth there is great interest in public health research and Dr. Jobst works closely with The Dartmouth Institute and the Health Promotion Research Center at Dartmouth to implement programs such as HOBSCOTCH to a broad rural patient population.

After developing HOBSCOTCH and validating its effectiveness, the team at Dartmouth is now performing a follow up study to test and distribute HOBSCOTCH at other centers, including Maine Medical Center, the University of Vermont Medical Center, and the University of Massachusetts Medical School.  The team is also developing a virtual form of HOBSCOTCH that can be accessed over the web and implemented remotely to patients.  Cost-effectiveness with be examined for both versions of the HOBSCOTCH program.   

 

Selected publications:

Connolly AC, Sha L, Guntupalli JS, Oosterhof N, Halchenko YO, Nastase SA, di Oleggio Castello MV, Abdi H, Jobst BC, Gobbini MI, Haxby JV.  How the Human Brain Represents Perceived Dangerousness or "Predacity" of Animals.  J Neurosci.  2016 May 11;26(19):5373-84.

Jobst BC.  Bottom-of-Sulcus Dysplasia as an Epileptic Syndrome:  The Power of Clinical Correlation.  Epilepsy Currents.  2015 Nov-Dec; 15(6):325-326.
Thomas GP, Jobst BC.   Critical review of the responsive neurostimulator system for epilepsy.  Med Devices (Auckl).  2015 Oct 1;8:405-11.

Jobst BC.  Equal but Different?  MRI-Guided Stereotactic Laser Amygdalohippocampectomy and Traditional Temporal Lobe Surgery.  Epilepsy Currents.  2015 Sep-Oct;15(5):250-2.

Jobst BC.  Consensus Over Individualism:  Validation of the ILAE Definition for Drug Resistant Epilepsy.  Epilepsy Currents.  2015 July-Aug; 15(4):172-3.

Jobst BC, Engle J Jr.  Is it time to replace epileptic spikes with fast ripples?  Neurology.  2015 Jul 14;85(2):114-5.

King-Stephens D, Mirro E, Weber PB, Laxer KD, Van Ness PC, Salanova V, Spencer DC, Heck CN, Goldman A, Jobst B, Shields DC, Bergey GK, Eisenschenk S, Worrell GA, Rossi MA, Gross RE, Cole AJ, Sperling MR, Nair DR, Gwinn RP, Park YD, Rutecki PA, Fountain NB, Wharen RE, Hirsch LJ, Miller IO, Barkley GL, Edwards JC, Geller EB, Berg MJ, Sadler TL, Sun FT, Morrell MJ.  Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography.  Epilepsia.  2015 June;56(6):959-67.

Jobst BC, Cascino GDSurgical treatment for drug-resistant epilepsy—reply.  JAMA.  2015 Apr 21;313(15):1572-3. 

Quigg M, Sun F, Fountain NB, Jobst BC, Wong VS, Mirro E, Brown S, Spencer DC.  Interrater reliability in interpretation of electrocorticographic seizure detections of the responsive neurostimulator.  Epilepsia.  2015 Apr 20.

Jobst BC.  Beyond pills, machines and surgery:  rehabilitation after epilepsy surgery.  Epilepsy Curr.  2015 Jan-Feb;15(1):28-9.

Jobst BC, Cascino GD.  Resective epilepsy surgery for drug-resistant focal epilepsy:  a review.  JAMA.  2015 Jan 20;313(3):285-93.

Bergey GK, Morrell MJ, Mizrahi EM, Goldman A, King-Stephens D, Nair D, Srinivasan, S, Jobst B, Gross RE, Shields DC, Barkley G, Salanova V, Olejniczak P, Cole A, Cash SS, Noe K, Wharen R, Worrell G, Murro AM, Edwards J, Duchowny M, Spencer D, Smith M, Geller E, Gwinn R, Skidmore C, Eisenschenk S, Berg M, Heck C, Van Ness P, Fountain N, Rutecki P, Massey A, O'Donovan C, Labar D, Duckrow RB, Hirsch, LJ, Courtney T, Sun FT, Seale CG.  Long-term treatment with responsive brain stimulation in adults with refractory partial seizures.  Neurology.  2015 Feb 24;84(8):810-7.

Chen JJ, Caller TA, Mecchella JN, Tahkur DS, Homa K, Finn CT, Kobylarz EJ, Bujarski KA, Thadani VM, Jobst BC.  Reducing Severity of Comorbid Psychiatric Symptoms in an Epilepsy Clinic using Co-location Model:  Results of a Pilot Intervention.  Epilepsy Behav.  2014;39:92-6.

Caller TA, Chen JJ, Harrington JJ, Bujarski KA, Jobst BC.  Predictors for readmissions after video-EEG monitoring.  Neurology.  2014 Jul 29;83(5):450-5.

Selected Abstracts and Presentations

Jobst B.  Long-Term Outcome of Adults with Medically Intractable Neocortical Seizures Treated with Brain Responsive Neurostimulation. Abstract No. 3337, Poster presented at the American Academy of Neurology Annual 2016 Meeting, Vancouver, BC, Canada, April 15 – 21, 2016, www.aan.com.

Jobst B.  Circadian Patterns of Epileptiform Discharges Differ by Seizure Onset Location During Chronic, Long-Term Intracranial Monitoring.  Abstract No. 2662, Poster presented at the American Academy of Neurology Annual 2016 Meeting, Vancouver, BC, Canada, April 15 – 21, 2016, www.aan.com.

Roth, R.M., Abecassis, M., Pelletier, C.L., Caller, T.A., Alexandre, F.P., Jobst, B.C. (2016). Self-rated executive dysfunction in adults with focal epilepsy. Poster presented at the 44th Annual Meeting of the International Neuropsychological Society, Boston, February 2016.

Roth, R.M., Pelletier, C.L., Abecassis, M., Erdodi, L., Caller, T.A., Alexandre, F.P., Jobst, B.C. RBANS embedded effort measures in adults with focal epilepsy. Poster presented at the 44th Annual Meeting of the International Neuropsychological Society, Boston, February 2016.

G. P. Thomas, A. Titiz, P. Lenck-Santini, B. Jobst.  A Virtual Morris Water Maze; A Method to Study Allocentric Memory in Humans.  Abstract No. 2.221, American Epilepsy Society Annual 2015 Meeting, Philadelphia, PA, Dec 4 – 8, 2015, www.aesnet.org.

P. Van Ness, E. Mizrahi, D. King-Stephens, D. Nair, C. Bazil, R. Goodman, B. Jobst, R. Gross, D. Shields, G. L. Barkley, V. Salanova, G. Bergey, R. Wharen, G. Worrell, R. Marsh, K. Noe, A. M. Murro, A. Cole, J. C. Edwards, D. Spencer, M. Smith, E. Geller, R. Gwinn, C. Skidmore, M. Berg, C. Heck, M. Agostini, N. Fountain, P. Rutecki, A. Herekar, R. Duckrow, T. Crowder Skarpaas, R. Kapur, M. Morrell.  Long-term Outcome of Adults with Medically Intractable Mesial Temporal Lobe Seizures Treated with Responsive Neurostimulation.  Abstract No. 2.172, American Epilepsy Society Annual 2015 Meeting, Philadelphia, PA, Dec 4 – 8, 2015, www.aesnet.org

B. Jobst, R. Kapur, G. L. Barkley, M. Berg, G. Bergey, S. Cash, A. Cole, M. Duchowny, R. Duckrow, N. Fountain, R. Gross, R. Gwinn, A. Herekar, D. King-Stephens, I. Miller, A. Murro, D. Nair, K. Noe, M. A. Rossi, P. Rutecki, C. Skidmore, D. Spencer, W. Tatum, R. Wharen, G. Worrell, M. Morrell.  Long-term outcome of adults with medically intractable frontal lobe seizures treated with responsive neurostimulation.  Abstract No. 1.060, American Epilepsy Society Annual 2015 Meeting, Philadelphia, PA, Dec 4 – 8, 2015, www.aesnet.org.

David Spencer, Felice Sun, Sarah N. Brown, Barbara C. Jobst, Nathan B. Fountain, Victoria S. Wong, Emily A. Mirro, Mark Quigg.  Circadian Patterns of Epileptiform Activity from Long-term Intracranial Recordings in Ambulatory Subjects.  Abstract No. 1.036, American Epilepsy Society Annual 2015 Meeting, Philadelphia, PA, Dec 4 – 8, 2015, www.aesnet.org.

Caller T, Jobst BC. Impact of a screening tool on management of psychosocial comorbidities in persons with epilepsy. Abstract No 1.216, 2012, American Epilepsy Society Annual Meeting, www.aesnet.org.

Related MEW publications

Caller TA, Secore KL, Ferguson RJ, Roth RM, Alexandre FP, Henegan PL, Harrington JJ, & Jobst JC. Design and feasibility of a memory intervention with focus on self-management for cognitive impairment in epilepsy. Epilepsy & Behavior 44 (2015): 192-194.
View  PubMed Abstract

Caller TA, Secore KL, Ferguson RJ, Roth RM, Secore KL, Alexandre FP, Zhao W, Tosteson T,Henegan PL, Birney K & Jobst JC.(2016). A cognitive-behavioral intervention (HOBSCOTCH) improves quality of life and attention in epilepsy: a pilot study.  Epilepsy & Behavior, 57(Pt A):111-7.
doi: 10.1016/j.yebeh.2016.01.024

Kobau R, Cui W, Kadima N, Zack MM, Sajatovic M, Kaiboriboon, Jobst B.(2014). Tracking psychosocial health in adults with epilepsy—Estimates from the 2010 National Health Interview Survey, Epilepsy Behav. 41:66-73.
doi:10.1016/j.yebeh.2014.08.002
View PubMed Abstract

Sahoo S, Ramesh P, Welter E, Bukach A, Valdez J, Tatsuoka C, Bamps Y, Stoll S, Jobst B, Sajatovic M.(in press). Insight: An Ontology-based Integrated Database and Analysis Platform for Epilepsy Self-Management Research. International Journal of Medical Informatics

Related MEW interviews and presentations

Dr. Joseph Sirven, Professor of Neurology at Mayo Clinic Arizona and Editor-in-Chief of Epilepsy.com/Professionals, interviews Barbara Jobst, MD, Geisel School of Medicine at Dartmouth College of Medicine, about the HobScotch CDC Grant.

 

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